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Luspatercept, sold under the brand name Reblozyl, is a medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. [ 5 ] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication .
Luspatercept was shown to decrease the need for transfusions and this effect lasted for a median of 30.6 weeks. [ 51 ] [ 36 ] [ 52 ] HLA -matched allogeneic stem cell transplantation , particularly in younger (i.e. less than 40 years of age) and more severely affected patients, offers the potential for curative therapy.
Primary myelofibrosis (PMF) is a rare bone marrow blood cancer. [1] It is classified by the World Health Organization (WHO) as a type of myeloproliferative neoplasm, a group of cancers in which there is activation and growth of mutated cells in the bone marrow.
HRAs, QSEHRAs, and ICHRAS. Understanding the differences in eligible expenses between HRAs, QSEHRAs, and ICHRAs can help businesses determine which type of plan best fits their needs.
What Weight-Loss Related Spending Shifts Could Mean for Affected Industries. As long-term weight loss becomes more of a reality for many Americans, it's clear that they're envisioning lifestyle ...
The new king of Denmark has changed the country’s royal coat of arms to more prominently feature Greenland in an apparent rebuke of President-elect Donald Trump’s plan to take over the ...
Pacritinib, sold under the brand name Vonjo, is an anti-cancer medication used to treat myelofibrosis. [1] [2] It is a macrocyclic protein kinase inhibitor. It mainly inhibits Janus kinase 2 (JAK2) and Fms-like tyrosine kinase 3\CD135 (FLT3). Common side effects include diarrhea, low platelet counts, nausea, anemia, and swelling in legs. [2]
Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. Myelo refers to the bone marrow, proliferative describes the rapid growth of blood cells and neoplasm describes that growth as abnormal and uncontrolled.
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