Ad
related to: myelofibrosis clinical trialspfizerclinicaltrials.com has been visited by 10K+ users in the past month
Search results
Results from the WOW.Com Content Network
Primary myelofibrosis (PMF) is a rare bone marrow blood cancer. [1] It is classified by the World Health Organization (WHO) as a type of myeloproliferative neoplasm , a group of cancers in which there is activation and growth of mutated cells in the bone marrow .
Clinical trial results have been published for treatment of acute myeloid leukemia, [7] small cell lung cancer, [8] Hodgkin's lymphoma, [9] and myelodysplastic syndromes. [10] Teva halted a phase III trial in patients with lung cancer before it had begun, citing "business decisions" as the reason. [11]
Momelotinib, sold under the brand name Ojjaara among others, is an anticancer medication used for the treatment of myelofibrosis. [3] It is a Janus kinase inhibitor and it is taken by mouth. [3] The most common adverse reactions include dizziness, fatigue, bacterial infection, hemorrhage, thrombocytopenia, diarrhea, and nausea. [6]
GSK's new drug application (NDA) for momelotinib is under standard FDA review, with a decision expected on Jun 16, 2023.
Phase II clinical trials for multiple myeloma and myelofibrosis reported 'promising results'. [ 22 ] [ 23 ] Phase III results showed significant extension of progression-free survival , and overall survival (median 11.9 months vs. 7.8 months; p = 0.0002) in patients taking pomalidomide and dexamethasone vs. dexamethasone alone.
Ruxolitinib (sold under the brand names Jakafi and Jakavi among others, and as Opzelura in cream form) is a medication used for the treatment of intermediate or high-risk myelofibrosis, [6] a type of myeloproliferative neoplasm that affects the bone marrow; [11] [12] polycythemia vera, when there has been an inadequate response to or intolerance of hydroxyurea; [6] [13] and steroid-refractory ...
Myeloproliferative neoplasms (MPNs) are a group of rare blood cancers in which excess red blood cells, white blood cells or platelets are produced in the bone marrow. Myelo refers to the bone marrow, proliferative describes the rapid growth of blood cells and neoplasm describes that growth as abnormal and uncontrolled.
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Ad
related to: myelofibrosis clinical trialspfizerclinicaltrials.com has been visited by 10K+ users in the past month