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Luspatercept, sold under the brand name Reblozyl, is a medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. [ 5 ] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication .
Luspatercept was shown to decrease the need for transfusions and this effect lasted for a median of 30.6 weeks. [ 51 ] [ 36 ] [ 52 ] HLA -matched allogeneic stem cell transplantation , particularly in younger (i.e. less than 40 years of age) and more severely affected patients, offers the potential for curative therapy.
Primary myelofibrosis (PMF) is a rare bone marrow blood cancer. [1] It is classified by the World Health Organization (WHO) as a type of myeloproliferative neoplasm, a group of cancers in which there is activation and growth of mutated cells in the bone marrow.
Experts explain whether ice or heat for back pain will lead to better relief, and the best time to use each.
Myelophthisis can occur in the setting of chronic myeloproliferative disease (e.g. myelofibrosis), leukemia, lymphoma, and metastatic carcinoma or myeloma. It is common in people who have chronic idiopathic myelofibrosis. It has been linked to small-cell lung cancer, breast cancer or prostate cancer that metastasizes to the bone marrow. [2]
In his first public response to the consumer outcry following the fatal shooting of one of his top executives, UnitedHealth Group CEO Andrew Witty said Friday that the US health system “is not ...
A 24-year-old California man was electrocuted and died while hanging Christmas lights on Thursday, according to officials. Antonio Pascual was hanging Christmas lights the morning of Nov. 21 on a ...
Acceleron Pharma, Inc. is an American clinical stage biopharmaceutical company based in Cambridge, Massachusetts with a broad focus on developing medicines that regulate the transforming growth factor beta (TGF-β) superfamily of proteins, which play fundamental roles in the growth and repair of cells and tissues such as red blood cells, muscle, bone, and blood vessels.
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