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URA3 is often used in yeast research as a "marker gene", that is, a gene to label chromosomes or plasmids. URA3 encodes Orotidine 5'-phosphate decarboxylase (ODCase) , which is an enzyme that catalyzes one reaction in the synthesis of pyrimidine ribonucleotides (a component of RNA ).
In yeast and bacteria, OMP decarboxylase is a single-function enzyme.However, in mammals, OMP decarboxylase is part of a single protein with two catalytic activities.This bifunctional enzyme is named UMP synthase and it also catalyzes the preceding reaction in pyrimidine nucleotide biosynthesis, the transfer of ribose 5-phosphate from 5-phosphoribosyl-1-pyrophosphate to orotate to form OMP.
The yeast deletion project, formally the Saccharomyces Genome Deletion Project, is a project to create data for a near-complete collection of gene-deletion mutants of the yeast Saccharomyces cerevisiae. Each strain carries a precise deletion of one of the genes in the genome. This allows researchers to determine what each gene does by comparing ...
Hoda Kotb has big plans for life after Today. A co-anchor of the popular morning show since 2018 (and co-host of Today With Hoda & Jenna), Kotb is walking away from the prestigious gig on Jan. 10 ...
For their study, the researchers focused on thousands of so-called "variants of uncertain significance," or VUS, which show up on genetic tests but have yet to be characterized, leaving patients ...
Today Show hosts celebrated meteorologist Dylan Dreyer’s exciting announcement during the morning show Monday, Jan. 7. Through rain and shine, the children’s author and mother of three ...
A selectable marker is a gene introduced into cells, especially bacteria or cells in culture, which confers one or more traits suitable for artificial selection.They are a type of reporter gene used in laboratory microbiology, molecular biology, and genetic engineering to indicate the success of a transfection or transformation or other procedure meant to introduce foreign DNA into a cell.
Attorneys for President-elect Donald Trump and his allies have unleashed a legal blitz this week to prevent the release of special counsel Jack Smith's final report on his classified documents and ...