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Common side effects include loss of appetite, gastrointestinal upset, constipation, and low blood calcium. [1] These polymers are derived from polystyrene by the addition of sulfonate functional groups. Sodium polystyrene sulfonate was approved for medical use in the United States in 1958. [1]
Hypokalemia, hypomagnesaemia, nausea or vomiting are side effects commonly seen when polystyrene resins are used. Cases of colonic necrosis have been reported, particularly when sodium polystyrene sulfonate was used in combination with the laxative sorbitol. Additionally, electrolyte disturbances, systemic alkalosis or gastric irritation may occur.
Measures to remove potassium from the body include diuretics such as furosemide, potassium-binders such as polystyrene sulfonate (Kayexalate) and sodium zirconium cyclosilicate, and hemodialysis. [1] Hemodialysis is the most effective method. [3] Hyperkalemia is rare among those who are otherwise healthy. [6]
These methods include polystyrene microspheres, nanoparticles, and solid foams. In the biomedical engineering field, these methods assist researchers in drug delivery, diagnostics, and imaging strategies. [1] [2] A common group of medication that utilizes a combination of polystyrene and sulfonate functional groups are polystyrene sulfonates. [3]
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