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It happens over time and can be due to the effects of aging, overuse of a joint, or injury. Then there’s inflammatory arthritis. This category of arthritis is the result of an inflammatory ...
While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. [1] The underlying mechanism involves the body's immune system attacking the joints. [1] This results in inflammation and thickening of the joint capsule. [1] It also affects the underlying bone and cartilage. [1]
Rheumatoid arthritis (RA) is a disorder in which the body's own immune system starts to attack body tissues. [72] The attack is not only directed at the joint but to many other parts of the body. In rheumatoid arthritis, most damage occurs to the joint lining and cartilage which eventually results in erosion of two opposing bones.
Rheumatoid arthritis and psoriatic arthritis have a different cause. Dr. Kteleh explains that both of these types of arthritis are caused by inflammation stemming from an autoimmune condition.
Women are 2–3 times more susceptible than men. The prevalence of rheumatoid lung disease in patients with RA depends on the method used for diagnosis: chest X rays (5%), high resolution CT scans (10–40%). [6] A study showed 582 patients with RA and 603 subjects without RA were followed for a mean of 16.4 and 19.3 years, respectively.
The inflammatory mediators of RA including cytokines, growth factors, metalloproteinases destroy articular cartilage, subchondral bone, tendons and ligaments. Destructive synovitis leads to bone erosion and causes the ligaments of the spine to become too laxed (loose), eventually resulting in cervical spinal instability (loose neck bones). [6]
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