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Approximately three people must be treated with low-dose capsaicin cream for one person to experience significant pain relief (number needed to treat =3.3). [2] [8] A single topical application of a high-dose capsaicin patch over the affected area after numbing the area with a topical anesthetic has also been found to relieve PHN-associated ...
Capsaicin is used as an analgesic in topical ointments and dermal patches to relieve pain, typically in concentrations between 0.025% and 0.1%. [16] It may be applied in cream form for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, backache, strains and sprains, often in compounds with other ...
Bengay and similar products, such as Flexall, Mentholatum, Capzasin and Icy Hot, variously contain menthol, methyl salicylate (oil of wintergreen), and capsaicin as active ingredients and have a potential to cause first-to-third-degree chemical burns. [4] [5] Some people have been hospitalized after receiving such burns. [4]
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Numerous capsaicin-containing creams are available over the counter, containing low concentrations of capsaicin (0.025 - 0.075%). It is debated whether these preparations actually lead to TRPV1 desensitization; it is possible that they act via counter-irritation.
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