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Organic indigestion is the result of an underlying disease, such as gastritis, peptic ulcer disease (an ulcer of the stomach or duodenum), or cancer. [6] Functional indigestion (previously called non-ulcer dyspepsia) [ 7 ] is indigestion without evidence of underlying disease. [ 8 ]
In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.
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The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus , stomach , and intestines .
Gastrointestinal physiology is the branch of human physiology that addresses the physical function of the gastrointestinal (GI) tract.The function of the GI tract is to process ingested food by mechanical and chemical means, extract nutrients and excrete waste products.
A fourth phase of acid secretion is known as the basal state which occurs in the times between meals (interdigestive phase). The level of acid secretion during these times is regulated by body weight, individual, number of parietal cells, and time of day. Acid secretion is lowest in the morning before awakening and highest at night. [2]
Heartburn has different triggers, including certain foods, medications, obesity, and stress. These triggers are different for each individual. These triggers are different for each individual. Gastroesophageal reflux disease or GERD is a chronic condition that can lead to more serious complications like esophageal cancer . [ 33 ]