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By NMR-guided simulations, amyloid beta 1-40 and amyloid beta 1-42 also seem to feature highly different conformational states, [66] with the C-terminus of amyloid beta 1-42 being more structured than that of the 1-40 fragment. Low-temperature and low-salt conditions allowed to isolate pentameric disc-shaped oligomers devoid of beta structure. [67]
p3 peptide also known as amyloid β- peptide (Aβ) 17–40/42 is the peptide resulting from the α-and γ-secretase cleavage from the amyloid precursor protein . It is known to be the major constituent of diffuse plaques observed in Alzheimer's disease (AD) brains and pre- amyloid plaques in people affected by Down syndrome .
The notions of completely and absolutely monotone function/sequence play an important role in several areas of mathematics. For example, in classical analysis they occur in the proof of the positivity of integrals involving Bessel functions or the positivity of Cesàro means of certain Jacobi series. [ 6 ]
Amyloid beta (Aβ) is a small protein, most often 40 or 42 amino acids in length, that is released from a longer parent protein called the Aβ-precursor protein (APP). [24] APP is produced by many types of cell in the body, but it is especially abundant in neurons. It is a single-pass transmembrane protein, passing once through cellular ...
In mathematics, some functions or groups of functions are important enough to deserve their own names. This is a listing of articles which explain some of these functions in more detail. There is a large theory of special functions which developed out of statistics and mathematical physics.
Let {f n} be a sequence of functions analytic on a simply-connected domain S. Suppose there exists a compact set Ω ⊂ S such that for each n , f n ( S ) ⊂ Ω. Forward (inner or right) Compositions Theorem — { F n } converges uniformly on compact subsets of S to a constant function F ( z ) = λ .
In mathematics, more specifically in general topology and related branches, a net or Moore–Smith sequence is a function whose domain is a directed set. The codomain of this function is usually some topological space. Nets directly generalize the concept of a sequence in a metric space.
The snake lemma is a tool used in mathematics, particularly homological algebra, to construct long exact sequences.The snake lemma is valid in every abelian category and is a crucial tool in homological algebra and its applications, for instance in algebraic topology.