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Ergotamine/caffeine, sold under the brand name Cafergot among others, is a fixed-dose combination medication used for the treatment of migraine. It contains ergotamine , as the tartrate, an alpha adrenergic blocking agent; and caffeine , a cranial vasoconstrictor.
High doses of caffeine (750 to 1200 mg/day spread throughout the day) have been shown to produce complete tolerance to some, but not all of the effects of caffeine. Doses as low as 100 mg/day, such as a 6 oz (170 g) cup of coffee or two to three 12 oz (340 g) servings of caffeinated soft-drink, may continue to cause sleep disruption, among ...
DMPX (3,7-dimethyl-1-propargylxanthine) is a caffeine analog which displays affinity for A 2 adenosine receptors, in contrast to the A 1 subtype receptors. [1] DMPX had 28 times and 15 times higher potency than caffeine in blocking, respectively, the peripheral and central effects of the adenosine agonist NECA.
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The ECA stack is a drug combination used in weight loss and as a stimulant.ECA is an initialism for ephedrine, caffeine, and aspirin, with variants of it including the EC stack, which removes the aspirin for those who can not tolerate it.
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Another example is Bex, a once popular Australian compound analgesic which is no longer sold. It contained 42% aspirin, 42% phenacetin, plus caffeine. [2]The United States Food and Drug Administration also now requires that manufacturers of compound analgesics unequivocally state each ingredient's purpose.
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