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The exposome is a concept used to describe environmental exposures that an individual encounters throughout life, and how these exposures impact biology and health. It encompasses both external and internal factors, including chemical, physical, biological, and social factors that may influence human health. [1] [2] [3]
The Toxin and Toxin-Target Database (T3DB), [1] [2] also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets. The database currently houses nearly 3,700 toxic compounds or poisons described by nearly 42,000 synonyms.
Exposure science is the study of the contact between humans (and other organisms) and harmful agents within their environment – whether it be chemical, physical, biological, behavioural or mental stressors – with the aim of identifying the causes and preventions of the adverse health effects they result in. [1] [2] This can include exposure within the home, workplace, outdoors or any other ...
Ancient history – Aggregate of past events from the beginning of recorded human history and extending as far as the Early Middle Ages or the Postclassical Era. The span of recorded history is roughly five thousand years, beginning with the earliest linguistic records in the third millennium BC in Mesopotamia and Egypt .
Here are nine of some of the most significant archaeological discoveries in history that changed what humans know about our origins and culture through time. Pompeii and Herculaneum gave a glimpse ...
The exposome encompasses the set of human environmental (i.e. non-genetic) exposures from conception onwards, complementing the genome. The exposome was first proposed in 2005 by cancer epidemiologist Christopher Paul Wild in an article entitled "Complementing the genome with an "exposome": the outstanding challenge of environmental exposure ...
Human history or world history is the record of humankind from prehistory to the present. Modern humans evolved in Africa around 300,000 years ago and initially lived as hunter-gatherers . They migrated out of Africa during the Last Ice Age and had spread across Earth's continental land except Antarctica by the end of the Ice Age 12,000 years ago.
Anatomically modern humans appear in Africa. [103] [104] [105] Around 50 ka they start colonising the other continents, replacing Neanderthals in Europe and other hominins in Asia. 70 ka Genetic bottleneck in humans (Toba catastrophe theory). 40 ka Last giant monitor lizards (Varanus priscus) die out. 35-25 ka Extinction of Neanderthals.