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Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.
Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Personal resources, such as status, social support, money, or shelter, may reduce or prevent an employee's emotional exhaustion. According to the Conservation of Resources theory (COR), people strive to obtain, retain and protect their personal resources, either instrumental (for example, money or shelter), social (such as social support or status), or psychological (for example, self-esteem ...
Physiological needs include: Air, Water, Food, Heat, Clothes, Reproduction, Shelter [22] and Sleep. Many of these physiological needs must be met for the human body to remain in homeostasis. Air, for example, is a physiological need; a human being requires air more urgently than higher-level needs, such as a sense of social belonging.
Substrate shortage is one of the causes of metabolic fatigue. Substrates are depleted during exercise or are unable to be metabolized (e.g. metabolic myopathies), resulting in a lack of intracellular energy sources to fuel contractions. In essence, the muscle stops contracting because it lacks the energy to do so.
In such cases, there is no anticipation of threat or harm present but still the result is fatigue. Characteristic of mental fatigue is difficulty focusing. For a mentally fatigued person, paying attention to something uninteresting is burdensome, even though focusing on something of great interest poses no particular challenge.
"Sick and Tired" is a song by American singer-songwriter Anastacia from her third studio album, Anastacia (2004). "Sick and Tired" was written by Anastacia, Dallas Austin , and Glen Ballard ; as a hook line, it samples vocals sung by Sohan Lal in Punjabi from the sample library "Deepest India" (also used in "Let the Music Play" by Italian music ...
"All the Tired Horses" is a song written by Bob Dylan, released on his 1970 double album Self Portrait. The song is the first track on the album. It is most notable for its absence of Dylan's singing. It consists of a small choir of female voices (Hilda Harris, Albertine Robinson, and Maeretha Stewart) [1] repeating the same two lines