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Metformin inhibits cyclic AMP production, blocking the action of glucagon, and thereby reducing fasting glucose levels. [117] Metformin also induces a profound shift in the faecal microbial community profile in diabetic mice, and this may contribute to its mode of action possibly through an effect on glucagon-like peptide-1 secretion. [108]
Aspen Pharmacare Holdings Limited is a public multinational pharmaceutical company headquartered in uMhlanga, South Africa. [7] Founded in 1997, [8] it listed on the Johannesburg Stock Exchange (JSE) in 1998, [9] and purchased South African Druggists in 1999 before expanding into international markets. [10]
The Bristol-Myers Squibb Company, doing business as Bristol Myers Squibb (BMS), is an American multinational pharmaceutical company.Headquartered in Princeton, New Jersey, [2] BMS is one of the world's largest pharmaceutical companies and consistently ranks on the Fortune 500 list of the largest U.S. corporations.
One analysis found that metformin “reduced cancer incidence and mortality in patients with diabetes, with overall cancer incidence reduced by 31 percent and cancer mortality reduced by 34 ...
A new cell study has shown the common type 2 diabetes medication metformin alters levels of microRNAs that target genes to slow down the growth and multiplication of colorectal cancer cells. The ...
Marksans Pharma Limited has recalled metformin hydrochloride extended-release tablets due to their excessive levels of NDMA, a “probable human carcinogen,” noted the Food and Drug ...
Abraxis BioScience was a global biopharmaceutical, and nano-medicine company that developed treatments for critically ill patients. It had over 2000 employees worldwide in 2007. [ 3 ] Abraxis's portfolio included the world's first protein-based nanoparticle chemotherapeutic compound , called nab Technology. [ 4 ]
Tower Cancer Research Foundation (TCRF) is a 501(c)(3) non-profit organization dedicated to clinical research, patient support and community education. It was established in 1996 in Beverly Hills, California.