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Landau–Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, [1] or aphasia with convulsive disorder, is a rare neurological syndrome that develops during childhood. [2] It is named after William Landau and Frank Kleffner, who characterized it in 1957 with a diagnosis of six children. [3] [4]
The use of this classification system imparts knowledge about the diagnostic profile of a child and the various contextual factors that may contribute to difficulties. [ 5 ] The DC: 0-5 functions as a reference for the earlier manifestations of problems in infants and children, which can be connected to later problems in functioning.
Aphasia, also known as dysphasia, [a] is an impairment in a person’s ability to comprehend or formulate language because of damage to specific brain regions. [2] The major causes are stroke and head trauma; prevalence is hard to determine, but aphasia due to stroke is estimated to be 0.1–0.4% in developed countries. [3]
[10] [11] [12] In the classical Mesulam criteria for primary progressive aphasia, there are two variants: a non-fluent type PNFA and a fluent type SD. [13] [14] A third variant of primary progressive aphasia, LPA was then added, [15] and is an atypical form of Alzheimer's disease. For PNFA, the core criteria for diagnosis include agrammatism ...
Specific language impairment (SLI) is diagnosed when a child's language does not develop normally and the difficulties cannot be accounted for by generally slow development, physical abnormality of the speech apparatus, autism spectrum disorder, apraxia, acquired brain damage or hearing loss.
Developmental Language Disorder (DLD) is identified when a child has problems with language development that continue into school age and beyond. The language problems have a significant impact on everyday social interactions or educational progress, and occur in the absence of autism spectrum disorder, intellectual disability or a known biomedical condition.
Anomic aphasia (word retrieval failures) Phonemic paraphasia (sound errors in speech e.g. 'gat' for 'cat') Agrammatism (using the wrong tense or word order) As the disease develops, speech quantity decreases and many patients become mute. Cognitive domains other than language are rarely affected early on.
The Boston Naming Test (BNT), introduced in 1983 by Edith Kaplan, Harold Goodglass and Sandra Weintraub, is a widely used neuropsychological assessment tool to measure confrontational word retrieval in individuals with aphasia or other language disturbance caused by stroke, Alzheimer's disease, or other dementing disorder. [1]