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Experts say that metformin and insulin can also be used together to help women with type 2 diabetes and gestational diabetes manage blood glucose levels during pregnancy. Metformin is just as safe ...
A total review of metformin use during pregnancy compared to insulin alone found good short-term safety for both the mother and baby, but safety in the longer term is unclear. [61] Several observational studies and randomized controlled trials found metformin to be as effective and safe as insulin for the management of gestational diabetes.
As with anything pregnancy-related, speaking to a healthcare provider is your best bet. They can assess your situation and explain your choices to help you find the best treatment plan.
Pre-gestational diabetes can be classified as Type 1 or Type 2 depending on the physiological mechanism. Type 1 diabetes mellitus is an autoimmune disorder leading to destruction of insulin-producing cell in the pancreas; type 2 diabetes mellitus is associated with obesity and results from a combination of insulin resistance and insufficient insulin production.
Metformin treatment in pregnancy is not safe. [91] In 2007, the Royal College of Obstetricians and Gynaecologists also recommended against the use of the drug to prevent miscarriage. [ 90 ] Thrombophilias or defects in coagulation and bleeding were once thought to be a risk of miscarriage but have been subsequently questioned. [ 92 ]
Generally speaking, GLP-1s, GIP/GLP-1s, and metformin are considered safe and effective when used as prescribed. That said, no medication is without side effects.
[1] [2] It is regarded as a second-line option compared to metformin, due to metformin's well-established safety and efficacy. [1] Use of glimepiride is recommended in conjunction with lifestyle modifications such as diet and exercise. [1] It is taken by mouth, [1] reaching a peak effect within three hours and lasting for about a day. [1]
Timing is everything for many things in life — including when to take medication like metformin, sold under the brand names Glucophage®, Fortamet®, Riomet®, and Glumetza®. 4 Tips for Knowing ...
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