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The US Food and Drug Administration (FDA) approved durvalumab for certain types of bladder, lung, and biliary tract cancer: [6] [13] [14]. Adults with locally advanced or metastatic urothelial carcinoma who either have disease progression during or following platinum-containing chemotherapy or have disease progression within twelve months of neoadjuvant or adjuvant treatment with platinum ...
However, he says you can often lower your risk of side effects by staying well hydrated, eating smaller meals, and limiting processed foods, high-fat foods, and refined carbohydrates.
Some drugs used for weight loss work by increasing energy expenditure. Two of the earliest weight loss drugs, 2,4-dinitrophenol and thyroid hormone, increase energy expenditure, but both were withdrawn from use due to risks. [8] Adrenergic agonists, especially those that work on the beta-2 adrenergic receptor, increase energy expenditure.
Listen to your body and take things slowly to avoid side effects from overeating. Make healthy swaps. Go for lean proteins , non-starchy vegetables, and whole grains if possible.
Mild calorie restriction may be beneficial for pregnant women to reduce weight gain (without weight loss) and reduce perinatal risks for both the mother and child. [11] [12] For overweight or obese individuals, calorie restriction may improve health through weight loss, although a gradual weight regain of 1–2 kg (2.2–4.4 lb) per year may occur.
Adults with mild type 2 diabetes might improve their insulin sensitivity by following a low-carb diet, thus potentially eliminating the need for medication, a new study suggests.
Low-calorie and very-low-calorie diets may produce faster weight loss within the first 1–2 weeks of starting compared to other diets, but this superficially faster loss is due to glycogen depletion and water loss in the lean body mass and is regained quickly afterward. [10]
The most common side effects of these drugs that led to withdrawals were mental disturbances, cardiac side effects, and drug abuse or drug dependence. Deaths were associated with seven products. [84] Ephedra was removed from the US market in 2004 over concerns that it raises blood pressure and could lead to strokes and death. [85]