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It’s also prescribed off-label for weight loss. While it’s not FDA-approved for this use, many healthcare professionals prescribe metformin as an effective weight loss drug when appropriate.
Of the diabetes drugs prescribed off-label for weight loss, metformin is one of the most well-researched. If you have obesity or are struggling to lose weight, talk to a healthcare provider about ...
When you’re motivated to lose weight and taking steps to make it happen, you want results — fast. But, unfortunately, weight loss takes time, even when you’re taking something like metformin ...
Metformin use is typically associated with weight loss. [69] It appears to be safe and effective in counteracting the weight gain caused by the antipsychotic medications olanzapine and clozapine. [70] [71] [72] Although modest reversal of clozapine-associated weight gain is found with metformin, primary prevention of weight gain is more ...
Metformin is preferred in overweight diabetics and for those gaining weight because taking clozapine for schizophrenia, as it may lead to mild weight loss in comparison to sulfonylureas or insulin. [ 60 ] [ 61 ] The thiazolidinediones , on the other hand, may cause weight gain, but decrease central obesity. [ 62 ]
It is often used off-label as a nootropic. Prazosin (Minipress) for nightmares: prazosin is approved for the use of hypertension. A 2012 systematic review showed a small benefit for the treatment of PTSD-associated night terrors. Other non-FDA-approved uses for prazosin include the treatment of Raynaud's disease and poisoning due to scorpion venom.
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