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Lipedema is a condition that is almost exclusively found in women [3] and results in enlargement of both legs due to deposits of fat under the skin. [2] Women of any weight may be affected [2] [3] and the fat is resistant to traditional weight-loss methods. [4]
Hypermetabolism is defined as an elevated resting energy expenditure (REE) > 110% of predicted REE. [1] Hypermetabolism is accompanied by a variety of internal and external symptoms, most notably extreme weight loss, and can also be a symptom in itself. This state of increased metabolic activity can signal underlying issues, especially ...
Clinical symptoms of RED-S may include disordered eating, fatigue, hair loss, cold hands and feet, dry skin, noticeable weight loss, increased healing time from injuries (e.g., lingering bruises), increased incidence of bone fracture and cessation of menses. [12] Affected athletes may also struggle with low self-esteem and depression.
The exact cause of lipodermatosclerosis is unknown. [3] [6] Venous disease, such as venous incompetence, venous hypertension, and body mass may be relevant to the underlying pathogenesis. [3] Increased blood pressure in the veins (venous hypertension) can cause diffusion of substances, including fibrin, out of capillaries.
The general explanation of increased infectious comorbidity in malnourished people is that (1) the immune system is what prevents such diseases from being more widespread in healthy, well-nourished people and (2) malnutrition stresses and diminishes immune function. In other words, malnutrition tends to cause (mild or moderate) immunodeficiency ...
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Irritable bowel syndrome, or IBS, is among the most common gastrointestinal conditions today. It affects some 10% to 15% of people in the U.S., per the American College of Gastroenterology. A ...
Schamberg's disease is a skin disorder that causes a discoloration of the lower extremities. [4] It usually occurs in the lower extremities and rarely elsewhere. [4] This condition is caused by leaky blood vessels near the surface of the skin. [7] The cause of the leaky capillaries is usually not known. [7]