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Detoxification (often shortened to detox and sometimes called body cleansing) is a type of alternative-medicine treatment which aims to rid the body of unspecified "toxins" – substances that proponents claim accumulate in the body over time and have undesirable short-term or long-term effects on individual health.
This occurs particularly in the subsurface environment and water sources, as well as in biological systems, having the potential to impact human health. [7] Some of the main sources of pollution and the introduction of xenobiotics into the environment come from large industries such as pharmaceuticals, fossil fuels, pulp and paper bleaching and ...
Cytochrome P450 oxidases are important enzymes in xenobiotic metabolism.. Xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as drugs and poisons.
Heavy metal detox, or detoxification, is the removal of toxic heavy metal substances from the body. In conventional medicine, detoxification can also be achieved artificially by techniques such as dialysis and (in a very limited number of cases) chelation therapy. There is a firm scientific base in evidence-based medicine for this treatment. [7]
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
Rotenone was used in powdered form to treat scabies and head lice on humans, and parasitic mites on chickens, livestock, and pet animals. In agriculture it was unselective in action and killed potato beetles , cucumber beetles , flea beetles , cabbage worms , raspberry beetles , and asparagus beetles , as well as most other arthropods.
Contamination of medicinal plants with mycotoxins can contribute to adverse human health problems and therefore represents a special hazard. [ 41 ] [ 42 ] Numerous natural occurrences of mycotoxins in medicinal plants and herbal medicines have been reported [ 43 ] [ 44 ] from various countries including Spain, China, Germany, India, Turkey and ...
This detoxification pathway is the result of multiple enzymes, with superoxide dismutases catalysing the first step and then catalases and various peroxidases removing hydrogen peroxide. As with antioxidant metabolites, the contributions of these enzymes to antioxidant defenses can be hard to separate from one another, but the generation of ...