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The test was first developed by Dr. Carol Barnes in 1979. [1] The test subjects are usually rodents such as mice or lab rats , which either serve as a control or may have some genetic variable or deficiency present in them which will cause them to react to the maze differently.
Systemic signs seem to be rare, but hepatosplenomegaly, thrombocytopenia and hyperbilirubinemia have been documented in a few cases, and skin blisters were reported in one infant. [7] If a woman has come into contact with a rodent during pregnancy and LCM symptoms are manifested, a blood test is available to determine previous or current infection.
The test was developed to study spatial learning and how it differed from other forms of associative learning. [11] Originally rats, now more commonly mice, were placed in an open pool and the latency to escape was measured for up to six trials a day for 2–14 days. [12] Several variables are used to evaluate an animal's performance.
The open field test can be used to assess memory by evaluating the ability of the animal to recognize a stimulus or object. Another animal test that is used to assess memory using that same concept is the novel object recognition test.
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Rodent mite dermatitis (also known as rat mite dermatitis) is an often unrecognized ectoparasitosis occurring after human contact with haematophagous mesostigmatid mites that infest rodents, such as house mice, [1] rats [2] and hamsters. [3]
Several factors can cause a person to have classic signs of dementia, including a deficiency in vitamin B12. This vitamin deficiency can cause forgetfulness and mimic symptoms of dementia—but it ...
If the patient can communicate, the mental status exam may give a reliable baseline for tracking dementia symptoms and memory loss. This exam measures a senior’s concentration, short-term recall ...
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