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Mederma is a topical product used to improve scar appearance. It is a gel based on an onion extract. Mederma is product of HRA Pharma, a division of Perrigo. A Mederma marketing claim is that the product can can make scars "softer, smoother, and less noticeable". [1]
The exact mechanism of action of silicone gel sheeting has not been fully studied. Currently, many proposed mechanisms explain the efficacy of such treatment, including the occlusion and hydration effect, increased body surface temperature, polarized electric charge, immunological effects, etc. [9] The occlusion and hydration effect is the most studied mechanism of action.
Silicone scar treatments are commonly used in preventing scar formation and improving existing scar appearance. [50] A meta-study by the Cochrane collaboration found weak evidence that silicone gel sheeting helps prevent scarring. [51] However, the studies examining it were of poor quality and susceptible to bias. [51]
Silicone rubber is an elastomer composed of silicone—itself a polymer—containing silicon together with carbon, hydrogen, and oxygen. Silicone rubbers are widely used in industry, and there are multiple formulations. Silicone rubbers are often one- or two-part polymers, and may contain fillers to improve properties or reduce cost.
Silicone caulk can be used as a basic sealant against water and air penetration. In organosilicon and polymer chemistry, a silicone or polysiloxane is a polymer composed of repeating units of siloxane (−O−R 2 Si−O−SiR 2 −, where R = organic group). They are typically colorless oils or rubber-like substances. Silicones are used in ...
RTV silicone rubber can be used to cast materials including wax, gypsum, low-melt alloys/metals, and urethane, epoxy, or polyester resins (without using a release agent). A more recent innovation is the ability to 3D print RTV silicones.
The products cure from a liquid or gel state to a solid elastomer. Curing entails crosslinking by the hydrolysis of silyl ethers: 2 RSi(OCH 3) 2 R' + H 2 O → [RSi(OCH 3)R'] 2 O + 2 CH 3 OH. In a hydrolysis reaction, a catalyst and moisture is required to form an intermediate silanol, which then reacts to form siloxane linkages in a ...
Silicone resin with R = CH 3, H or OH. Silicone resins are a type of silicone material which is formed by branched, cage-like oligosiloxanes with the general formula of R n SiX m O y, where R is a non-reactive substituent, usually methyl (Me = −CH 3) or phenyl (Ph = −C 6 H 5), and X is a functional group: hydrogen (−H), hydroxyl (−OH), chlorine (−Cl) or alkoxy (−O −).
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