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  2. Partial least squares regression - Wikipedia

    en.wikipedia.org/wiki/Partial_least_squares...

    Partial least squares (PLS) regression is a statistical method that bears some relation to principal components regression and is a reduced rank regression; [1] instead of finding hyperplanes of maximum variance between the response and independent variables, it finds a linear regression model by projecting the predicted variables and the observable variables to a new space of maximum ...

  3. Coefficient of determination - Wikipedia

    en.wikipedia.org/wiki/Coefficient_of_determination

    Ordinary least squares regression of Okun's law.Since the regression line does not miss any of the points by very much, the R 2 of the regression is relatively high.. In statistics, the coefficient of determination, denoted R 2 or r 2 and pronounced "R squared", is the proportion of the variation in the dependent variable that is predictable from the independent variable(s).

  4. Lean laboratory - Wikipedia

    en.wikipedia.org/wiki/Lean_laboratory

    A lean laboratory is one which is focused on processes, procedures, and infrastructure that deliver results in the most efficient way in terms of cost, speed, or both. Lean laboratory is a management and organization process derived from the concept of lean manufacturing and the Toyota Production System (TPS).

  5. Fisher's method - Wikipedia

    en.wikipedia.org/wiki/Fisher's_method

    Under Fisher's method, two small p-values P 1 and P 2 combine to form a smaller p-value.The darkest boundary defines the region where the meta-analysis p-value is below 0.05.. For example, if both p-values are around 0.10, or if one is around 0.04 and one is around 0.25, the meta-analysis p-value is around 0

  6. Partial least squares path modeling - Wikipedia

    en.wikipedia.org/wiki/Partial_least_squares_path...

    PLS-PM [4] [5] is a component-based estimation approach that differs from the covariance-based structural equation modeling.Unlike covariance-based approaches to structural equation modeling, PLS-PM does not fit a common factor model to the data, it rather fits a composite model.

  7. Non-linear least squares - Wikipedia

    en.wikipedia.org/wiki/Non-linear_least_squares

    Non-linear least squares is the form of least squares analysis used to fit a set of m observations with a model that is non-linear in n unknown parameters (m ≥ n). It is used in some forms of nonlinear regression. The basis of the method is to approximate the model by a linear one and to refine the parameters by successive iterations.

  8. Process analytical chemistry - Wikipedia

    en.wikipedia.org/wiki/Process_analytical_chemistry

    Process analytical chemistry (PAC) is the application of analytical chemistry with specialized techniques, algorithms, and sampling equipment for solving problems related to chemical processes. It is a specialized form of analytical chemistry used for process manufacturing similar to process analytical technology (PAT) used in the ...

  9. Quantitative structure–activity relationship - Wikipedia

    en.wikipedia.org/wiki/Quantitative_structure...

    Lead discovery using fragnomics is an emerging paradigm. In this context FB-QSAR proves to be a promising strategy for fragment library design and in fragment-to-lead identification endeavours. [18] An advanced approach on fragment or group-based QSAR based on the concept of pharmacophore-similarity is developed. [19]