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Pantoprazole has been found to pass through the breast milk. Additionally, in rodent cancer studies, pantoprazole has been shown to potentially cause tumor growth. The clinical relevance of the finding is unknown, but risks and benefits are recommended for consideration in determining the use of therapy for the mother and child. [18] [2]
Peptic ulcer disease including after endoscopic treatment for bleeding [11] As part of Helicobacter pylori eradication therapy [ 12 ] Gastroesophageal reflux disease (GERD or GORD) including symptomatic endoscopy-negative reflux disease [ 13 ] and associated laryngopharyngeal reflux causing laryngitis [ 14 ] and chronic cough [ 15 ]
About a third of older people with peptic ulcers have no symptoms. [1] Complications may include bleeding, perforation, and blockage of the stomach. [2] Bleeding occurs in as many as 15% of cases. [2] Common causes include infection with Helicobacter pylori and non-steroidal anti-inflammatory drugs (NSAIDs). [1]
Mallory–Weiss syndrome is a condition where high intra-abdominal pressures causes laceration and bleeding of the mucosa called Mallory-Weiss tears. [1] Additionally, Mallory–Weiss syndrome is one of the most common causes of acute upper gastrointestinal bleeding, counting of around 1-15% of all cases in adults and less than 5% in children.
Treatment is guided by the severity and specific cause of the disease. Treatment focuses on eliminating the underlying problem, whether that means discontinuing drugs suspected to cause it or treating underlying sepsis. Diagnosis and treatment of serious thrombocytopenia is usually directed by a hematologist.
The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.
The stick is applied directly to the bleeding site. The high ionic strength promotes flocculation of the blood, and the astringent chemical causes local vasoconstriction. Before safety razors were invented, a styptic pencil was a standard part of a shaving kit and was used to seal shaving cuts. [ 13 ]
"Medical bleeding" denotes hemorrhage as a result of an underlying medical condition (i.e. causes of bleeding that are not directly due to trauma). Blood can escape from blood vessels as a result of 3 basic patterns of injury: [citation needed] Intravascular changes — changes of the blood within vessels (e.g. ↑ blood pressure, ↓ clotting ...
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