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There are three clinical phenotypes: relapsing-remitting MS (RRMS), characterized by periods of neurological worsening following by remissions; secondary-progressive MS (SPMS), in which there is gradual progression of neurological dysfunction with fewer or no relapses; and primary-progressive MS (MS), in which neurological deterioration is ...
Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.
Main symptoms of multiple sclerosis Symptoms and findings in multiple sclerosis. Multiple sclerosis can cause a variety of symptoms varying significantly in severity and progression among individuals: changes in sensation (hypoesthesia), muscle weakness, abnormal muscle spasms, or difficulty moving; difficulties with coordination and balance; problems in speech or swallowing (), visual ...
“Estrogen, particularly estradiol, the strongest form, plays a critical role in the brain’s health and functionality, earning it the title of the ‘master regulator’ of women’s brain health.
Abundant extracellular myelin in the meninges of patients with multiple sclerosis has been found [118] Brain tissues with MRI-hidden problems are usually named Normal Appearing. Exploring the normal-appearing corpus callosum has been found a possible primary hypoperfusion, [119] according with other findings in this same direction.
Malignant MS cases are not common, less than 5% of patients with MS experience this type of progression. [2] The National MS Society Advisory Committee on Clinical Trials of New Agents consensus defined it as: disease with a rapid progressive course, leading to significant disability in multiple neurologic systems or death in a relatively short ...
Christina Applegate. Christina Applegate shed new light on her battle with multiple sclerosis (MS).. When it comes to updates, the 52-year-old actress has been on a roll lately, frankly speaking ...
(primary progressive MS) One year of disease progression (retrospectively or prospectively determined) and Two of the following: One or more T2-hyperintense lesions characteristic of multiple sclerosis in one or more of the following brain regions: periventricular, cortical or juxtacortical, or infratentorial
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