Search results
Results from the WOW.Com Content Network
Body surface area. In physiology and medicine, the body surface area ( BSA) is the measured or calculated surface area of a human body. For many clinical purposes, BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass. Nevertheless, there have been several important critiques of the ...
Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs ( chemotherapeutic agents or alkylating agents) in a standard regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim only to prolong life or ...
Clark's rule. Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [ 1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK ...
The absolute bioavailability is the dose-corrected area under curve ( AUC) non-intravenous divided by AUC intravenous. The formula for calculating the absolute bioavailability, F, of a drug administered orally (po) is given below (where D is dose administered). Therefore, a drug given by the intravenous route will have an absolute ...
A dose–response curve is a coordinate graph relating the magnitude of a dose (stimulus) to the response of a biological system. A number of effects (or endpoints) can be studied. The applied dose is generally plotted on the X axis and the response is plotted on the Y axis. In some cases, it is the logarithm of the dose that is plotted on the ...
The surface area of an adult is about 20,900 square centimeters (3,240 sq in) and the surface area of a child of 6 years is about 9,000 square centimeters (1,400 sq in). These figures and figures for other body parts or portions can be found in the EPA (Environmental Protection Agency) Exposures Handbook 1996 [ 22 ] or estimated using other ...
In single dosage scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose. In drugs where multiple doses of treatment are needed in a day, the physician must take into account information regarding the total amount of the drug which is safe to use in one day, and how that ...
Absorption (pharmacology) Absorption is the journey of a drug travelling from the site of administration to the site of action. [ 1 ][ 2 ] The drug travels by some route of administration ( oral, topical-dermal, etc.) in a chosen dosage form (e.g., tablets, capsules, or in solution ). [ 3 ] Absorption by some other routes, such as intravenous ...