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Body surface area. In physiology and medicine, the body surface area ( BSA) is the measured or calculated surface area of a human body. For many clinical purposes, BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass. Nevertheless, there have been several important critiques of the ...
Clark's rule. Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [ 1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK ...
Dosage of chemotherapy can be difficult: If the dose is too low, it will be ineffective against the tumor, whereas, at excessive doses, the toxicity (side-effects) will be intolerable to the person receiving it. [4] The standard method of determining chemotherapy dosage is based on calculated body surface area (BSA).
The Lund and Browder chart is a tool useful in the management of burns for estimating the total body surface area affected. It was created by Dr. Charles Lund, Senior Surgeon at Boston City Hospital, and Dr. Newton Browder, based on their experiences in treating over 300 burn victims injured at the Cocoanut Grove fire in Boston in 1942. [ 1]
The surface area of an adult is about 20,900 square centimeters (3,240 sq in) and the surface area of a child of 6 years is about 9,000 square centimeters (1,400 sq in). These figures and figures for other body parts or portions can be found in the EPA (Environmental Protection Agency) Exposures Handbook 1996 [ 22 ] or estimated using other ...
A dose is a measured quantity of a medicine, nutrient, or pathogen which is delivered as a unit. The greater the quantity delivered, the larger the dose. Doses are most commonly measured for compounds in medicine. The term is usually applied to the quantity of a drug or other agent administered for therapeutic purposes, but may be used to ...
Pharmacokinetics is based on mathematical modeling that places great emphasis on the relationship between drug plasma concentration and the time elapsed since the drug's administration. Pharmacokinetics is the study of how an organism affects the drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism.
Total body surface area. Total body surface area ( TBSA) is an assessment of injury to or disease of the skin, such as burns or psoriasis . In adults, the Wallace rule of nines can be used to determine the total percentage of area burned for each major section of the body. [ 1]