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Dextromethorphan (DXM), sold under the trade name Robitussin among others, is a cough suppressant used in many cough and cold medicines. [6] In 2022, the US Food and Drug Administration (FDA) approved the combination dextromethorphan/bupropion to serve as a rapid-acting antidepressant in patients with major depressive disorder .
As a cough suppressant, the polistirex version lasts up to 12 hours. This duration also holds true when used recreationally. In 1981, a paper by Gosselin estimated that the lethal dose is between 50 and 500 mg/kg. Doses as high as 15–20 mg/kg are taken by some recreational users.
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Robitussin cough syrup is being recalled due to microbial contamination that can lead to fungemia. Honey flavors are included in the 2024 recall.
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Dextromethorphan is a cough suppressant found in several cold medications. Several U.S. states have begun regulating who, and under what circumstances, can purchase dextromethorphan containing products. Not all states have regulations documented at this time, but this article contains all the states that have documentation.
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914 Williams Ave, Columbus, OH · Directions · (614) 545-3190