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  2. Methods to investigate protein–protein interactions - Wikipedia

    en.wikipedia.org/wiki/Methods_to_investigate...

    Proteinprotein docking, the prediction of proteinprotein interactions based only on the three-dimensional protein structures from X-ray diffraction of protein crystals might not be satisfactory. [44] [45] Network analysis includes the analysis of interaction networks using methods of graph theory or statistical methods.

  3. Protein–protein interaction prediction - Wikipedia

    en.wikipedia.org/wiki/Proteinprotein...

    Proteinprotein interaction prediction is a field combining bioinformatics and structural biology in an attempt to identify and catalog physical interactions between pairs or groups of proteins. Understanding proteinprotein interactions is important for the investigation of intracellular signaling pathways, modelling of protein complex ...

  4. List of protein subcellular localization prediction tools

    en.wikipedia.org/wiki/List_of_protein_sub...

    This list of protein subcellular localisation prediction tools includes software, databases, and web services that are used for protein subcellular localization prediction. Some tools are included that are commonly used to infer location through predicted structural properties, such as signal peptide or transmembrane helices , and these tools ...

  5. Interactome - Wikipedia

    en.wikipedia.org/wiki/Interactome

    In molecular biology, an interactome is the whole set of molecular interactions in a particular cell.The term specifically refers to physical interactions among molecules (such as those among proteins, also known as proteinprotein interactions, PPIs; or between small molecules and proteins [1]) but can also describe sets of indirect interactions among genes (genetic interactions).

  6. Protein–protein interaction - Wikipedia

    en.wikipedia.org/wiki/Proteinprotein_interaction

    The protein protein interactions are displayed in a signed network that describes what type of interactions that are taking place [74] Proteinprotein interactions often result in one of the interacting proteins either being 'activated' or 'repressed'. Such effects can be indicated in a PPI network by "signs" (e.g. "activation" or "inhibition").

  7. STRING - Wikipedia

    en.wikipedia.org/wiki/STRING

    Exploring the predicted interaction networks can suggest new directions for future experimental research and provide cross-species predictions for efficient interaction mapping. [7] Proteinprotein interaction network visualized by STRING. In this view, the color saturation of the edges represents the confidence score of a functional association

  8. Protein subcellular localization prediction - Wikipedia

    en.wikipedia.org/wiki/Protein_subcellular...

    The aim is to build tools that can accurately predict the outcome of protein targeting in cells. Prediction of protein subcellular localization is an important component of bioinformatics based prediction of protein function and genome annotation, and it can aid the identification of drug targets.

  9. Protein–protein interaction screening - Wikipedia

    en.wikipedia.org/wiki/Proteinprotein...

    Methods that screen proteinprotein interactions in the living cells. Bimolecular fluorescence complementation (BiFC) is a technique for observing the interactions of proteins. Combining it with other new techniques, dual expression recombinase based methods can enable the screening of proteinprotein interactions and their modulators. [1]