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Franklin was a physical chemist who made pivotal research in the discovery of the structure of DNA, known as "the most important discovery" in biology. [1] [2] DNA itself had become "life's most famous molecule". [3] While working at the King's College London in 1951, she discovered two types of DNA called A-DNA and B-DNA. Her X-ray images of ...
[224] [225] Her work was a crucial part in the discovery of DNA's structure, which, along with subsequent related work, led to Francis Crick, James Watson, and Maurice Wilkins being awarded a Nobel Prize in 1962. [226] Franklin had died in 1958, and during her lifetime, the DNA structure was not considered to be fully proven.
James D. Watson; The Double Helix: A Personal Account of the Discovery of the Structure of DNA, Atheneum, 1980, ISBN 0-689-70602-2 (first published in 1968) is a very readable firsthand account of the research by Crick and Watson.
DNA model built by Crick and Watson in 1953, in the Science Museum, London. In mid-March 1953, Watson and Crick deduced the double helix structure of DNA. [11] Crucial to their discovery were the experimental data collected at King's College London—mainly by Rosalind Franklin for which they did not provide proper attribution.
The double-helix model of DNA structure was first published in the journal Nature by James Watson and Francis Crick in 1953, [6] (X,Y,Z coordinates in 1954 [7]) based on the work of Rosalind Franklin and her student Raymond Gosling, who took the crucial X-ray diffraction image of DNA labeled as "Photo 51", [8] [9] and Maurice Wilkins, Alexander Stokes, and Herbert Wilson, [10] and base-pairing ...
The DNA structure at left (schematic shown) will self-assemble into the structure visualized by atomic force microscopy at right. DNA nanotechnology is the field that seeks to design nanoscale structures using the molecular recognition properties of DNA molecules.
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It is not always the case that the structure of a molecule is easy to relate to its function. What makes the structure of DNA so obviously related to its function was described modestly at the end of the article: "It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material".