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The middle region is a mostly fibrous portion. It consists of two layers: the endosteal layer, which lies closest to the skull, and the inner meningeal layer, which lies closer to the brain. [7] It contains larger blood vessels that split into the capillaries in the pia mater. It is composed of dense fibrous tissue, and its inner surface is ...
Endothelium lines the inner wall of vessels, shown here. Microscopic view showing endothelium (at top) inside the heart. The endothelium forms an interface between circulating blood or lymph in the lumen and the rest of the vessel wall. This forms a barrier between vessels and tissues and control the flow of substances and fluid into and out of ...
The three layers of a blood vessel are an inner layer (the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica externa). In dissection , the inner coat (tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small pieces; but, because of its friability ...
The dura mater has two layers, an outer periosteal layer closely adhered to the neurocranium, and an inner meningeal layer known as the dural border cell layer. [1] The two dural layers are for the most part fused together forming a thick fibrous tissue membrane that covers the brain and the vertebrae of the spinal column. [2]
The arachnoid mater makes arachnoid villi, small protrusions through the dura mater into the venous sinuses of the brain, which allow CSF to exit the subarachnoid space and enter the blood stream. Unlike the dura mater, which receives a rich vascular supply from numerous arteries, the arachnoid mater is avascular (lacking blood vessels).
The outer layer is the tunica adventitia and the thickest layer in veins. It is entirely made of connective tissue. It also contains nerves that supply the vessel as well as nutrient capillaries (vasa vasorum) in the larger blood vessels.
The membrane in this area is much thicker than the cranial pia mater, due to the two-layer composition of the pia membrane. The outer layer, which is made up of mostly connective tissue, is responsible for this thickness. Between the two layers are spaces which exchange information with the subarachnoid cavity as well as blood vessels.
Two circulations joining at the circle of Willis (inferior view) Diagram showing features of cerebral outer membranes and supply of blood vessels. The internal carotid arteries supply oxygenated blood to the front of the brain and the vertebral arteries supply blood to the back of the brain. [55]