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The spinothalamic tract is a nerve tract in the anterolateral system in the spinal cord. [1] This tract is an ascending sensory pathway to the thalamus . From the ventral posterolateral nucleus in the thalamus, sensory information is relayed upward to the somatosensory cortex of the postcentral gyrus .
The spinohypothalamic tract or spinohypothalamic fibers is a sensory fiber tract projecting from the spinal cord to the hypothalamus directly to mediate reflex autonomic and endocrine responses to painful stimuli (the hypothalamus receives additional indirect nociceptive projections from the reticular formation (see: spinoreticular tract), and periaqueductal gray (see: spinomesencephalic tract).
The region affected includes the descending corticospinal tract, ascending spinothalamic tract, and autonomic fibers. It is characterized by a corresponding loss of motor function, loss of pain and temperature sensation, and hypotension. Anterior spinal artery syndrome is the most common form of spinal cord infarction. [1]
The spinomesencephalic pathway, spinomesencephalic tract or spino-quadrigeminal system of Mott, includes a number of ascending tracts in the spinal cord, including the spinotectal tract. [1] [2] [3] The spinomesencephalic tract is one of the ascending tracts in the anterolateral system of the spinal cord that projects to various parts of the ...
The ventral posterior nucleus receives neuronal input from the medial lemniscus, spinothalamic tracts, and trigeminothalamic tract. It projects to the somatosensory cortex and the ascending reticuloactivation system.
These fibers are part of a pathway which may be implicated in central sensitization in chronic pain conditions. Fibers synapsing on these laminae that release peptides SST and GDNF may be part of a pathway that inhibits pain signaling. [2] Some of the SGR projects to the marginal nucleus of the spinal cord, or lamina I, and laminae III-V. Most ...
The neurons located here receive input primarily from Lissauer's tract and relay information related to pain and temperature sensation. [1] [2] Pain sensation relayed here cannot be modulated, e.g. pain from burning the skin. The axons of neurons contribute to the lateral spinothalamic tract. [3] [4]
The ventral posteromedial nucleus (VPM) is a nucleus within the ventral posterior nucleus of the thalamus and serves an analogous somatosensory relay role for the ascending trigeminothalamic tracts as its lateral neighbour the ventral posterolateral nucleus serves for dorsal column–medial lemniscus pathway 2nd-order neurons.