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The IC 50 of a drug can be determined by constructing a dose-response curve and examining the effect of different concentrations of antagonist on reversing agonist activity. IC 50 values can be calculated for a given antagonist by determining the concentration needed to inhibit half of the maximum biological response of the agonist. [ 4 ]
The response factor can be expressed on a molar, volume or mass [1] basis. Where the true amount of sample and standard are equal: = where A is the signal (e.g. peak area) and the subscript i indicates the sample and the subscript st indicates the standard. [2]
sc is a cross-platform, free, TUI, spreadsheet and calculator application that runs on Unix and Unix-like operating systems. It has also been ported to Windows. It can be accessed through a terminal emulator, and has a simple interface and keyboard shortcuts resembling the key bindings of the Vim text editor. It can be used in a similar manner ...
A Shock Response Spectrum (SRS) [1] is a graphical representation of a shock, or any other transient acceleration input, in terms of how a Single Degree Of Freedom (SDOF) system (like a mass on a spring) would respond to that input. The horizontal axis shows the natural frequency of a hypothetical SDOF, and the vertical axis shows the peak ...
ACR score is a scale to measure change in rheumatoid arthritis symptoms. [1] It is named after the American College of Rheumatology.The ACR score is more often used in clinical trials than in doctor patient-relationships, as it allows a common standard between researchers.
If the response data used to estimate the model contain values that change sign, or if the lowest response value is far from zero (for example, when data are left-truncated), a location parameter, L, may be added to the response so that the expressions for the quantile function and for the median become, respectively:
The RPI is used to assess whether the bone marrow is producing an appropriate response to an anemic state. Reticulocyte production should increase in response to any loss of red blood cells. It should increase within 2–3 days of a major acute hemorrhage, for instance, and reach its peak in 6–10 days. [3]
Showing, from top to bottom, the original impulse, the response after high frequency boosting, and the response after low frequency boosting. In signal processing and control theory, the impulse response, or impulse response function (IRF), of a dynamic system is its output when presented with a brief input signal, called an impulse (δ(t ...