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  2. Bottom–up and top–down design - Wikipedia

    en.wikipedia.org/wiki/Bottom–up_and_topdown...

    Illustration of bottom up and top down approach to heap sort. Bottom–up and top–down are both strategies of information processing and ordering knowledge, used in a variety of fields including software, humanistic and scientific theories (see systemics), and management and organization. In practice they can be seen as a style of thinking ...

  3. Top-down - Wikipedia

    en.wikipedia.org/wiki/Top-down

    Top-down and bottom-up design of information ordering; Top-down parsing, a parsing strategy beginning at the highest level of the parse tree Top-down parsing language, an analytic formal grammar to study top-down parsers; Top-down perspective, a camera angle in computer and video games; Top-down shooter, a subgenre of video games

  4. Top-down proteomics - Wikipedia

    en.wikipedia.org/wiki/Top-down_proteomics

    Top-down vs bottom-up proteomics. Top-down proteomics is a method of protein identification that either uses an ion trapping mass spectrometer to store an isolated protein ion for mass measurement and tandem mass spectrometry (MS/MS) analysis [1] [2] or other protein purification methods such as two-dimensional gel electrophoresis in conjunction with MS/MS. [3] Top-down proteomics is capable ...

  5. Bottom-up - Wikipedia

    en.wikipedia.org/wiki/Bottom-up

    Bottom-up integration testing, in software testing; Top-down and bottom-up design, strategies of information processing and knowledge ordering; Bottom-up proteomics, a laboratory technique involving proteins; Bottom Up Records, a record label founded by Shyheim; Bottom-up approach of the Holocaust, a viewpoint on the causes of the Holocaust

  6. Hierarchical clustering - Wikipedia

    en.wikipedia.org/wiki/Hierarchical_clustering

    Agglomerative: This is a "bottom-up" approach: Each observation starts in its own cluster, and pairs of clusters are merged as one moves up the hierarchy. Divisive: This is a "top-down" approach: All observations start in one cluster, and splits are performed recursively as one moves down the hierarchy.

  7. Bottom-up parsing - Wikipedia

    en.wikipedia.org/wiki/Bottom-up_parsing

    Top-down parsing eagerly decides what a construct is much earlier, when it has only scanned the leftmost symbol of that construct and has not yet parsed any of its parts. Left corner parsing is a hybrid method that works bottom-up along the left edges of each subtree, and top-down on the rest of the parse tree.

  8. Bottom-up proteomics - Wikipedia

    en.wikipedia.org/wiki/Bottom-up_proteomics

    There is limited protein sequence coverage by identified peptides, loss of labile PTMs, and ambiguity of the origin for redundant peptide sequences. [7] Recently the combination of bottom-up and top-down proteomics, so called middle-down proteomics, is receiving a lot of attention as this approach not only can be applied to the analysis of large protein fragments but also avoids redundant ...

  9. Nanotechnology - Wikipedia

    en.wikipedia.org/wiki/Nanotechnology

    Two main approaches are used in nanotechnology. In the "bottom-up" approach, materials and devices are built from molecular components which assemble themselves chemically by principles of molecular recognition. [24] In the "top-down" approach, nano-objects are constructed from larger entities without atomic-level control. [25]