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The treatment of a real-world population consisting of individuals with Alzheimer’s and co-occurring conditions is thus likely to lead to more adverse events or reduced efficacy.
An estimated 6.7 million Americans ages 65 and older were living with Alzheimer’s in 2023, according to the Alzheimer’s Association. The number is projected to increase to 13.8 million by 2060.
The team compared 2019 Medicare dementia diagnoses in people 66 and older in each region with the number of expected new cases in that geographical area based on potentially modifiable risk ...
It is nominally under the auspices of the California Health and Human Services Agency. It is headquartered in Sacramento. [2] As of September 2024, the California Department of Aging is being led by director Susan DeMarois. [3] DeMarois previously served as the Director of Public Policy and Advocacy for the Alzheimer's Association. [4]
The Alzheimer's Disease Cooperative Study (ADCS) was founded at University of California San Diego in 1991 and coordinates clinical trials of candidate treatments for Alzheimer's disease. It is funded by the National Institutes of Health as well as companies that develop drugs.
Early onset familial Alzheimer's disease can be attributed to mutations in one of three genes: those encoding amyloid-beta precursor protein (APP) and presenilins PSEN1 and PSEN2. [40] Most mutations in the APP and presenilin genes increase the production of a small protein called amyloid beta (Aβ)42, which is the main component of amyloid ...
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