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Nanotechnology is often defined as the study of materials and devices with features on a scale below 100 nanometers. DNA nanotechnology, specifically, is an example of bottom-up molecular self-assembly, in which molecular components spontaneously organize into stable structures; the particular form of these structures is induced by the physical ...
The success of DNA nanotechnology in constructing artificially designed nanostructures out of nucleic acids such as DNA, combined with the demonstration of systems for DNA computing, has led to speculation that artificial nucleic acid nanodevices can be used to target drug delivery based upon directly sensing its environment. These methods make ...
Single-stranded and double-stranded versions of these materials have been created using, for example, DNA, LNA, and RNA. One- and two-dimensional forms of nucleic acids (e.g., single strands, linear duplexes, and plasmids ) (Fig. 1) are important biological machinery for the storage and transmission of genetic information .
Many methods for encoding data in DNA are possible. The optimal methods are those that make economical use of DNA and protect against errors. [6] If the message DNA is intended to be stored for a long period of time, for example, 1,000 years, it is also helpful if the sequence is obviously artificial and the reading frame is easy to identify.
For example, DNA nanotechnology or cellular engineering would be classified as bionanotechnology because they involve working with biomolecules on the nanoscale. Conversely, many new medical technologies involving nanoparticles as delivery systems or as sensors would be examples of nanobiotechnology since they involve using nanotechnology to ...
The first reports of a double helix molecular model of B-DNA structure were made by James Watson and Francis Crick in 1953. [5] [6] That same year, Maurice F. Wilkins, A. Stokes and H.R. Wilson, reported the first X-ray patterns of in vivo B-DNA in partially oriented salmon sperm heads. [7]
Vicki Colvin Director for the Center for Biological and Environmental Nanotechnology, Rice University; Eric Drexler - was the first to theorise about nanotechnology in depth and popularised the subject; Richard Feynman - gave the first mention of some of the distinguishing concepts in a 1959 talk, entitled There's Plenty of Room at the Bottom
An example is a sensor having a switch approximately 1.5 nanometers across, able to count specific molecules in the chemical sample. The first useful applications of nanomachines may be in nanomedicine. For example, [9] biological machines could be used to identify and destroy cancer cells.