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Protein folding problem: Is it possible to predict the secondary, tertiary and quaternary structure of a polypeptide sequence based solely on the sequence and environmental information? Inverse protein-folding problem: Is it possible to design a polypeptide sequence which will adopt a given structure under certain environmental conditions?
A solution in radicals or algebraic solution is an expression of a solution of a polynomial equation that is algebraic, that is, relies only on addition, subtraction, multiplication, division, raising to integer powers, and extraction of n th roots (square roots, cube roots, etc.). A well-known example is the quadratic formula
In the case of two nested square roots, the following theorem completely solves the problem of denesting. [2]If a and c are rational numbers and c is not the square of a rational number, there are two rational numbers x and y such that + = if and only if is the square of a rational number d.
Radical extensions occur naturally when solving polynomial equations in radicals.In fact a solution in radicals is the expression of the solution as an element of a radical series: a polynomial f over a field K is said to be solvable by radicals if there is a splitting field of f over K contained in a radical extension of K.
The quadratic formula =. is a closed form of the solutions to the general quadratic equation + + =. More generally, in the context of polynomial equations, a closed form of a solution is a solution in radicals; that is, a closed-form expression for which the allowed functions are only n th-roots and field operations (+,,, /).
is the simplest equation that cannot be solved in radicals, and that almost all polynomials of degree five or higher cannot be solved in radicals. The impossibility of solving in degree five or higher contrasts with the case of lower degree: one has the quadratic formula, the cubic formula, and the quartic formula for degrees two, three, and ...
Chain propagation: A radical reacts with a non-radical to produce a new radical species; Chain termination: Two radicals react with each other to create a non-radical species; In a free-radical addition, there are two chain propagation steps. In one, the adding radical attaches to a multiply-bonded precursor to give a radical with lesser bond ...
Radical disproportionation encompasses a group of reactions in organic chemistry in which two radicals react to form two different non-radical products. Radicals in chemistry are defined as reactive atoms or molecules that contain an unpaired electron or electrons in an open shell. The unpaired electrons can cause radicals to be unstable and ...
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