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[4] [5] Bromazolam is a non subtype selective agonist at the benzodiazepine site of GABA A receptors, with a binding affinity of 2.81 nM at the α 1 subtype, 0.69 nM at α 2 and 0.62 nM at α 5. [6] The "common" dosage range for users of bromazolam was reported to be 1–2 mg, suggesting its potency is similar to alprazolam.
Benzyl bromide is an organic compound with the formula C 6 H 5 CH 2 Br. The molecule consists of a benzene ring substituted with a bromomethyl group. It is a colorless liquid with lachrymatory properties. The compound is a reagent for introducing benzyl groups. [3] [4]
All three have been synthesized by various routes: 1-Bromo-2-chlorobenzene: from 2-chloroaniline, via diazotization followed by a Sandmeyer reaction [1]; 1-Bromo-3-chlorobenzene: by (3-chlorophenyl)trimethylgermanium by electrophilic substitution [2] [better source needed]
This reagent can be used, e.g. in the reaction with carbon dioxide to prepare benzoic acid. [4] Other methods involve palladium-catalyzed coupling reactions , such as the Suzuki reaction . Bromobenzene is used as a precursor in the manufacture of phencyclidine .
Benzyl chloroformate, also known as benzyl chlorocarbonate or Z-chloride, is the benzyl ester of chloroformic acid. It can be also described as the chloride of the benzyloxycarbonyl (Cbz or Z) group. In its pure form it is a water-sensitive oily colorless liquid, although impure samples usually appear yellow.
4,4’-Dichlorobenzophenone is prepared by the acylation of chlorobenzene with 4-chlorobenzoyl chloride. The conversion is typically conducted in the presence of an aluminium chloride catalyst in a petroleum ether solvent. ClC 6 H 5 C(O)Cl + C 6 H 5 Cl → (ClC 6 H 4) 2 CO + HCl
Halazone (4-(dichlorosulfamoyl)benzoic acid) is a chemical compound whose formula can be written as either C 7 H 5 Cl 2 NO 4 S or (HOOC)(C 6 H 4)(SO 2)(NCl 2). It has been widely used to disinfect drinking water. Other names for this compound include p-sulfondichloramidobenzoic acid, 4-[(dichloroamino)sulfonyl]benzoic acid, and Pantocide.
[2] [3] [5] Hatakabb was created to mass-produce the medicines for sale. [2] [3] [5] Owing to growing sales of its products, the company established a factory in Bang Khun Thian district on Rama II Road. [3] Hatakabb was run in 2007 by the second generation of the family: Suthep Simawara as board chair and Suthep and Sunthon Simawara as co ...