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The signs and symptoms of hypopituitarism vary, depending on which hormones are undersecreted and on the underlying cause of the abnormality. The diagnosis of hypopituitarism is made by blood tests, but often specific scans and other investigations are needed to find the underlying cause, such as tumors of the pituitary, and the ideal treatment ...
This usually occurs in the presence of a tumor of the pituitary, although in 80% of cases this has not been diagnosed previously. The most common initial symptom is a sudden headache , often associated with a rapidly worsening visual field defect or double vision caused by compression of nerves surrounding the gland.
As magnetic resonance imaging became more available diagnosis increased dramatically. [16] At this time it is believed that the disease is far more prevalent than is diagnosed. [ 7 ] Nevertheless, autoimmune hypophysitis is frequently referred to as a rare disease and the most recent estimates as to its prevalence give it a value of around 5 ...
Evidence for prevalence of pain in newly diagnosed cancer is scarce. One study found pain in 38 percent of people who were newly diagnosed, another found 35 percent of such people had experienced pain in the preceding two weeks, while another reported that pain was an early symptom in 18–49 percent of cases.
Dr. Narayanan says that bone pain can also be a sign of prostate cancer recurrence in patients who have already had the disease. The link between prostate cancer and bone pain may be a surprising one.
Pressure on the kidney or ureter from a tumor outside the kidney can cause extreme flank pain. [7] Local recurrence of cancer after the removal of a kidney can cause pain in the lumbar back, or L1 or L2 spinal nerve pain in the groin or upper thigh, accompanied by weakness and numbness of the iliopsoas muscle, exacerbated by activity. [4]
In some cases, a woman with Sheehan syndrome may be relatively asymptomatic initially; therefore, the diagnosis would not be made until years later when features of hypopituitarism become evident. [7] In rare instances this syndrome can present acutely with unstable vital signs, dangerously low blood glucose levels, heart failure, or even ...
There are many causes of AHH, mostly due to structural lesions or functional abnormalities involving the HPG axis such as sarcoidosis, lymphocytic hypophysitis, pituitary adenomas, craniopharyngiomas and other CNS tumours. Most of these patients have multiple pituitary hormone deficiencies. [12] Hyperprolactinaemia is the