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Primordial soup, also known as prebiotic soup, is the hypothetical set of conditions present on the Earth around 3.7 to 4.0 billion years ago. It is an aspect of the heterotrophic theory (also known as the Oparin–Haldane hypothesis) concerning the origin of life, first proposed by Alexander Oparin in 1924, and J. B. S. Haldane in 1929.
Since then, the primordial soup theory (Oparin–Haldane hypothesis) has become the foundation in the study of abiogenesis. [88] [89] [90] Although Oparin's theory became widely known only after the English version in 1936, Haldane accepted Oparin's originality and said, "I have very little doubt that Professor Oparin has the priority over me ...
Robert Shapiro has summarized the "primordial soup" theory of Oparin and Haldane in its "mature form" as follows: [32] The early Earth had a chemically reducing atmosphere. This atmosphere, exposed to energy in various forms, produced simple organic compounds ("monomers").
The mathematical model on which these tables were based, though considerably revised and modified, remains a widely accepted method of decompressing divers from non-saturation exposures. In 1908, Haldane published the findings with A. E. Boycott and G. C. C. Damant in the paper "Prevention of Compressed-Air Illness" in the Journal of Hygiene. [4]
Although neutral evolution remains the consensus theory among modern biologists, [3] and thus Kimura's resolution of Haldane's dilemma is widely regarded as correct, some biologists argue that adaptive evolution explains a large fraction of substitutions in protein coding sequence, [4] and they propose alternative solutions to Haldane's dilemma.
Alexander Oparin in 1924 and J. B. S. Haldane in 1929 proposed that the first molecules constituting the earliest cells slowly self-organized from a primordial soup, and this theory is called the Oparin–Haldane hypothesis.
Haldane's sieve is particularly relevant in situations where the effects of natural selection are strong and the beneficial mutations have a significant impact on an organism's fitness. According to Haldane's sieve, when a new advantageous mutation arises in a population, it initially occurs as a single copy (a de novo mutation ), borne by an ...
The primordial soup theory of the origin of life, proposed by Alexander Oparin in Russian in 1924 (published in English in 1936) [9] and by J.B.S. Haldane in 1929, [10] suggested that life was preceded by the formation of what Haldane called a "hot dilute soup" of "colloidal organic substances", and which Oparin referred to as 'coacervates ...