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4-Toluenesulfonyl chloride (p-toluenesulfonyl chloride, toluene-p-sulfonyl chloride) is an organic compound with the formula CH 3 C 6 H 4 SO 2 Cl. This white, malodorous solid is a reagent widely used in organic synthesis. [2] Abbreviated TsCl or TosCl, it is a derivative of toluene and contains a sulfonyl chloride (−SO 2 Cl) functional group.
The environmental and toxicological effects of toluene have been extensively studied. [45] Toluene is irritating to the eyes, skin, and respiratory tract. It is absorbed slowly through the skin. It can cause systemic toxicity by inhalation or ingestion. Inhalation is the most common route of exposure.
p-Toluenesulfonic acid (PTSA, pTSA, or pTsOH) or tosylic acid (TsOH) is an organic compound with the formula CH 3 C 6 H 4 SO 3 H.It is a white extremely hygroscopic solid that is soluble in water, alcohols, and other polar organic solvents. [6]
RELATED: What your eyes say about your health "Since patients oftentimes require multiple treatments and overexposure to this, light can be potentially dangerous to your vision," she continued.
Hippuric acid has long been used as an indicator of toluene exposure; [14] however, there appears to be some doubt about its validity. [15] There is significant endogenous hippuric acid production by humans; which shows inter- and intra-individual variation influenced by factors such as diet, medical treatment, alcohol consumption, etc. [15] This suggests that hippuric acid may be an ...
Toluene (or methylbenzene) is a common chemical found in chemistry laboratories. An alkylbenzene is a chemical compound that contains a monocyclic aromatic ring attaching to one or more saturated hydrocarbon chains. [ 1 ]
A sulfonic acid can be thought of as sulfuric acid with one hydroxyl group replaced by an organic substituent. The parent compound (with the organic substituent replaced by hydrogen) is the parent sulfonic acid, HS(=O) 2 (OH), a tautomer of sulfurous acid, S(=O)(OH) 2. [a] Salts or esters of sulfonic acids are called sulfonates.
It is not known what the effects are from long-term ingestion or skin contact with low levels of cresols. The Occupational Safety and Health Administration has set a permissible exposure limit at 5 ppm (22 mg/m 3 ) over an eight-hour time-weighted average, while the National Institute for Occupational Safety and Health recommends a limit of 2.3 ...