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In this affidavit, Bugie stated that she was informed about streptomycin by Waksman and Shatz and had no part in the discovery of streptomycin. [18] Bugie was, however, later quoted by her daughters as having said that if the women's liberation movement had been present, she would have received credit towards the patent on streptomycin. [1]
Streptomycin, like streptothricin, possesses strong bactericidal properties, and preliminary experiments tended to indicate that the two substances are also comparable in their low toxicity to animals and in their in vivo activity. The various chemical and biological properties of streptomycin tend to point to this compound as one closely ...
Of these, streptomycin and neomycin found extensive application in the treatment of numerous infectious diseases. Streptomycin was the first antibiotic cure for tuberculosis (TB). In 1952 Waksman was the recipient of the Nobel Prize in Physiology or Medicine in recognition "for his discovery of streptomycin, the first antibiotic active against ...
However, these classifications are based on laboratory behavior. The development of antibiotics has had a profound effect on the health of people for many years. Also, both people and animals have used antibiotics to treat infections and diseases. In practice, both treat bacterial infections. [1]
Improvements in sanitation, vaccination, and other public-health measures began significantly reducing rates of tuberculosis even before the arrival of streptomycin and other antibiotics, although the disease remained a significant threat. [42] In 1946, the development of the antibiotic streptomycin made effective treatment and cure of TB a ...
Selman Abraham Waksman (July 22, 1888 – August 16, 1973) was a Jewish American inventor, Nobel Prize laureate, biochemist and microbiologist whose research into the decomposition of organisms that live in soil enabled the discovery of streptomycin and several other antibiotics.
Streptomyces is the largest genus of Actinomycetota, and the type genus of the family Streptomycetaceae. [3] Over 700 species of Streptomyces bacteria have been described. [4] [5] [6] As with the other Actinomycetota, streptomycetes are gram-positive, and have very large genomes with high GC content.
Additionally, 11 conserved signature proteins have been identified which are found in all sequenced Streptomyces species and K. setae. These proteins are believed to be unique to the Streptomycetales order, thus provide molecular markers which can be used to distinguish this group from the rest of the Actinomycetota.