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Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. [1] Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. [1] Other symptoms may include bone pain, chest pain, or itchiness. [1]
ICE in the context of chemotherapy is an acronym for one of the chemotherapy regimens, used in salvage treatment of relapsed or refractory non-Hodgkin's lymphoma and Hodgkin lymphoma. In case of CD20-positive B cell lymphoid malignancies the ICE regimen is often combined today with rituximab. This regimen is then called ICE-R or R-ICE or RICE.
Overall, CNS involvement is observed in 2 to 27% of patients with aggressive systemic non-Hodgkin’s lymphoma. [5] 5% of patients with diffuse large B cell lymphoma, the most common type of non-Hodgkin lymphoma, result in SCNSL but account for most SCNSL cases. [3] Illustration depicting metastasis by haematogenous spread
Non-Hodgkin lymphomas, which are defined as being all lymphomas except Hodgkin lymphoma, are more common than Hodgkin lymphoma. A wide variety of lymphomas are in this class, and the causes, the types of cells involved, and the prognoses vary by type. The number of cases per year of non-Hodgkin lymphoma increases with age.
[4] [5] At the 59th American Society of Hematology (ASH) Annual Meeting, interim results from a Phase I, open-label, single agent dose-escalating study designed to evaluate the treatment of camidanlumab tesirine in relapsed or refractory Hodgkin’s or non-Hodgkin’s lymphoma were presented. Among the patients enrolled at the time of the data ...
What is non-Hodgkin lymphoma? Non-Hodgkin lymphoma (sometimes simply called NHL) is a form of blood cancer that strikes the white blood cells of the infection-fighting lymphatic system.
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