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JSRV is the virus that is the cause of the contagious lung tumors in sheep called ovine pulmonary adenocarcinoma (OPA). The disease has also been called "jaagsiekte", after the Afrikaans words for "chase" (jaag) and "sickness" (siekte), to describe the respiratory distress observed in an animal out of breath from being chased, indicating the breathing difficulty experienced by infected sheep.
A collage of JSRV-infected sheep lung tumors. Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV).
Cache Valley virus infection; caprine arthritis encephalitis (CAE) enzootic nasal adenocarcinoma; foot-and-mouth disease; mastitis; Nairobi sheep disease orthonairovirus (NSDV) infection; orf, also known as contagious ecthyma, contagious pustular dermatitis, infectious labial dermatitis, thistle disease, sore mouth, or scabby mouth
[2] [3] The virus causes tumor growth in the upper nasal cavity and is closely related to JSRV which also causes respiratory tumors in ovine. [4] The disease, enzootic nasal adenocarcinoma is common in North America and is found in sheep and goats on every continent except New Zealand and Australia. [5]
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