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Branched chain amino acid transaminase 1 is a protein that in humans is encoded by the BCAT1 gene. [5] It is the first enzyme in the branched-chain amino acid (BCAA) degradation pathway and facilitates the reversible transamination of BCAAs and glutamate. BCAT1 resides in the cytoplasm, while its isoform, BCAT2, is found in the mitochondria.
BCAT1 is located in the mitochondria, BCAT2, 3, and 5 are located in chloroplasts, and BCAT4 and 6 are located in the cytoplasm of A. thaliana. [23] However, studies of BCATs in Solanum tuberosum (potato) revealed two isoforms that are 683 (BCAT1) and 746 (BCAT2) bp long located primarily in chloroplasts. [24]
Chromosome 12 is one of the 23 pairs of chromosomes in humans.People normally have two copies of this chromosome. Chromosome 12 spans about 133 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells.
Human protein-coding gene pages: •Python code for maintaining the list •List of human protein-coding genes page 1 covers genes A1BG–EPGN •List of human protein-coding genes page 2 covers genes EPHA1–MTMR3
IFR in between cloud layers in a Cessna 172. In aviation, instrument flight rules (IFR) is one of two sets of regulations governing all aspects of civil aviation aircraft operations; the other is visual flight rules (VFR).
VFR requires a pilot to be able to see outside the cockpit to control the aircraft's altitude, navigate, and avoid obstacles and other aircraft. [3] Governing agencies establish specific requirements for VFR flight, including minimum visibility, and distance from clouds, to ensure that aircraft operating under VFR are visible from enough distance to ensure safety.
Gabapentin is recommended for use in focal seizures and neuropathic pain. [7] [10] Gabapentin is prescribed off-label in the US and the UK, [22] [23] for example, for the treatment of non-neuropathic pain, [22] anxiety disorders, sleep problems and bipolar disorder. [24]
5575 19085 Ensembl ENSG00000188191 ENSMUSG00000025855 UniProt P31321 P12849 RefSeq (mRNA) NM_001164758 NM_001164759 NM_001164760 NM_001164761 NM_001164762 NM_002735 NM_001253890 NM_008923 NM_001359097 NM_001359098 NM_001359099 NM_001359100 NM_001359101 RefSeq (protein) NP_001158230 NP_001158231 NP_001158232 NP_001158233 NP_001158234 NP_002726 NP_001240819 NP_032949 NP_001346026 NP_001346027 NP ...