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The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans, it is a butterfly-shaped gland located in the neck below the Adam's apple. It consists of two connected lobes. The lower two thirds of the lobes are connected by a thin band of tissue called the isthmus (pl.: isthmi).
The thyroid gland is located in the front of the neck, in front of the thyroid cartilage, and is shaped like a butterfly, with two wings connected by a central isthmus. Thyroid tissue consists of follicles with a stored protein called colloid, containing[thyroglobulin], a precursor to other thyroid hormones, which are manufactured within the ...
The branches to the gland are generally two in number. One, the larger, supplies principally the anterior surface; on the isthmus of the gland it connects with the corresponding artery of the opposite side. A second branch descends on the posterior surface of the gland and anastomoses with the inferior thyroid artery. Besides the arteries ...
The isthmic organizer, or isthmus organizer, also known as the midbrain−hindbrain boundary (MHB), is a secondary organizer region that develops at the junction of the midbrain and metencephalon (embryonic hindbrain). [1] The MHB expresses signaling molecules that regulate the differentiation and patterning of the adjacent neuroepithelium.
One of the most important functions of the hypothalamus—it is located in the brain adjacent to the pituitary gland—is to link the endocrine system to the nervous system via the pituitary gland.) Other organs, such as the kidneys, also have roles within the endocrine system by secreting certain hormones.
This inferior end of the duct will then become the pyramidal lobe of the thyroid gland. The dividing cellular cords of the tubular duct become the isthmus and lateral lobes of the gland to complete the formation of the rest of the gland. [5] Once the thyroglossal duct involutes, the cells will begin to degenerate and disappear.
The hypothalamic–pituitary–thyroid axis (HPT axis for short, a.k.a. thyroid homeostasis or thyrotropic feedback control) is part of the neuroendocrine system responsible for the regulation of metabolism and also responds to stress. As its name suggests, it depends upon the hypothalamus, the pituitary gland, and the thyroid gland.
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