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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution; although, only in a few cases are genes the primary cause of obesity. [4] [5]
Monogenic obesity is excess weight caused by a mutation in a single gene, as opposed to syndromic obesity not tied to a single gene variation and most obesity, which is caused by multiple genetic and environmental risk factors. Monogenetic obesity mostly affects the hypothalamus and leptin–melanocortin system (see hypothalamic obesity ...
Obesity isn’t just a matter of food and exercise — it may be in your genetic code, according to new research. “Obesity’s causes are very complex and in the majority of cases, the ...
By 2015, no state had a prevalence of obesity under 18%; almost all states exceeded 22%, and six states exceeded 26%. [10] According to the Centers for Disease Control and Prevention (CDC), in 2016 the number of obese people in the United States reached an all-time high of about 93 million, up 33% from 2008. [ 11 ]
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In medicine, genetic susceptibility to a disease refers to a genetic predisposition to a health problem, [1] which may eventually be triggered by particular environmental or lifestyle factors, such as tobacco smoking or diet. Genetic testing is able to identify individuals who are genetically predisposed to certain diseases.
The main problem with this idea is the timing at which the transition is presumed to have happened, and how this would then translate into the genetic predisposition to type 2 diabetes and obesity [citation needed]. For example, the decline in reproductive investment in human societies (the so-called r to K shift) has occurred far too recently ...
WAGR syndrome (also known as WAGR complex, Wilms tumour-aniridia syndrome, aniridia-Wilms tumour syndrome) is a rare genetic syndrome in which affected children are predisposed to develop Wilms' tumour (a tumour of the kidneys), aniridia (absence of the coloured part of the eye, the iris), genitourinary anomalies, and mental retardation. [1]