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ICV injection of α-Interferon has been used for the treatment of intracranial malignancies in the clinic. α-Interferon has antiviral, antibacterial, and immunostimulatory properties. However, severe central nervous system symptoms occur after injection for ICV, intravenous, and intramuscular routes of administration.
Akinesia and anesthesia quickly ensue within minutes with a successful retrobulbar injection. Retrobulbar block can be used successfully for corneal transplantation but may require a supplemental facial nerve block. Retrobulbar block can block levator palpebrae muscle but not orbicularis oculi.
There are many types of SCID mice used by researchers at present. Some examples include SCID-hu Thy/Liv mice, which are given human fetal thymus and liver cells, hu-SRC-SCID mice, which are implanted with human hematopoietic stem cells (HSC), and hu-PBL-SCID mice, in which human peripheral blood mononuclear cells have been injected. [3]
In spaceflight an orbit insertion is an orbital maneuver which adjusts a spacecraft’s trajectory, allowing entry into an orbit around a planet, moon, or other celestial body. [1] An orbit insertion maneuver involves either deceleration from a speed in excess of the respective body's escape velocity, or acceleration to it from a lower speed.
Falcon 9 Block 5, the most prolific active orbital launch system in the world. This comparison of orbital launch systems lists the attributes of all current and future individual rocket configurations designed to reach orbit. A first list contains rockets that are operational or have attempted an orbital flight attempt as of 2024; a second list ...
Retrograde tracing can be achieved through various means, including the use of viral strains as markers of a cell's connectivity to the injection site. The pseudorabies virus (PRV; Bartha strain), for example, may be used as a suitable tracer due to the propensity of the infection to spread upstream through a pathway of synaptically linked ...
A mouse-human hybrid is a genetically modified mouse whose genome has both mouse and human genes, thus being a murine form of a human-animal hybrid. For example, genetically modified mice may be born with human leukocyte antigen genes in order to provide a more realistic environment when introducing human white blood cells into them in order to ...
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia, chemotherapy, or pain management. This route is also used to introduce drugs that fight ...