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The eclipse period is a variable period starting from HIV exposure in which no existing test can detect HIV. The median duration of the eclipse period in one study was 11.5 days. The window period is the time between HIV exposure and when an antibody or antigen test can detect HIV. The median window period for antibody/antigen testing is 18 days.
Pooled viral RNA testing shortens the window period to a median of 17 days (95% CI, 13-28 Days). [9] Although it is not the standard of care to use this test for diagnosis, in communities with high HIV prevalence, this test has a significantly improved negative predictive value over 3rd and 4th generation tests for detecting acute HIV infections.
With these tests, the window period is shorter, with an average duration of 12 days. [227] Fourth generation, or combination, HIV tests can detect HIV infection in 99% of individuals by one and a half months after infection. [232]
The window period for HIV may be up to three months, depending on the test method and other factors. RNA based HIV tests has the lowest window period. Modern and accurate testing abilities can cut this period to 25 days, 16 days, or even as low as 12 days, again, depending on the type of test and the quality of its administration and interpretation.
A negative test result does not confirm individuals are not infected by HIV. There is a window period of approximately 3 months when individuals are still not producing enough antibodies to generate a positive result, thus it is recommended to test regularly. [14] False positives. Lyme disease, syphilis, lupus, and other conditions can ...
People in the United States who have HIV and need kidney or liver transplants can now receive organs from donors who also have HIV without having to be part of a research study. A new federal rule ...
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