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Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
Urine of postmenopausal women reflects the hypergonadotropic state of menopause-levels of follicle stimulating hormone (FSH) and luteinizing hormone (LH) are high - and contain a mixture of these gonadotropins. [2] [3] [4] Other protein substances may be present, including small amounts of human chorionic gonadotropin (hCG). [1]
The presence of hCG in a woman's body indicates that a fertilized egg has implanted in the uterus and the placenta has started to form. 10 days after fertilization, significant hCG can be detected from woman's blood sample. [6] The levels of hCG in the body increase rapidly in the first few weeks of pregnancy, doubling every 48–72 hours. [7]
hMG (human Menopausal Gonadotrophins), FSH and LH prepared from human urine collected from postmenopausal women. First extracted in 1953. [3] Injected intra-muscularily (IM) or subcutaneously (SC). Generic. menotropins for injections, USP. Brands
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This image depicts how the hormone hCG, produced by pregnant women's placentas, is detected in urine pregnancy tests to indicate a positive result. Identified in the early 20th century, human chorionic gonadotropin (hCG) is a glycoprotein hormone that rises quickly in the first few weeks of pregnancy, typically reaching a peak at 8- to 10-weeks ...
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