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  2. Hypothetical types of biochemistry - Wikipedia

    en.wikipedia.org/wiki/Hypothetical_types_of...

    The genetic code may have evolved during the transition from the RNA world to a protein world. [86] The Alanine World Hypothesis postulates that the evolution of the genetic code (the so-called GC phase [87]) started with only four basic amino acids: alanine, glycine, proline and ornithine (now arginine). [88]

  3. Alanine world hypothesis - Wikipedia

    en.wikipedia.org/wiki/Alanine

    Alanine is the simplest α-amino acid after glycine. The methyl side-chain of alanine is non-reactive and is therefore hardly ever directly involved in protein function. [12] Alanine is a nonessential amino acid, meaning it can be manufactured by the human body, and does not need to be obtained through the diet. Alanine is found in a wide ...

  4. GADV-protein world hypothesis - Wikipedia

    en.wikipedia.org/wiki/GADV-protein_world_hypothesis

    GADV-protein world is a hypothetical stage of abiogenesis. GADV stands for the one letter codes of four amino acids , namely, glycine (G), alanine (A), aspartic acid (D) and valine (V), the main components of GADV proteins .

  5. Alanine scanning - Wikipedia

    en.wikipedia.org/wiki/Alanine_scanning

    In molecular biology, alanine scanning is a site-directed mutagenesis technique used to determine the contribution of a specific residue to the stability or function of a given protein. [1] Alanine is used because of its non-bulky, chemically inert, methyl functional group that nevertheless mimics the secondary structure preferences that many ...

  6. Nediljko Budisa - Wikipedia

    en.wikipedia.org/wiki/Nediljko_Budisa

    Along with Budisa's previous work on bioexpression using proline analogues, the results of this project contributed to the establishment of the Alanine World hypothesis. [26] It explains why nature chose the genetic code [27] with "only" 20 canonical amino acids for ribosomal protein synthesis. [28]

  7. World Hypotheses - Wikipedia

    en.wikipedia.org/wiki/World_Hypotheses

    We are immersed in a biological world of living organisms, both plants and animals, including ourselves. Living organisms are organized, self-regulating, and actively functioning systems. A seed planted in favorable conditions, unfolding and maturing into a tree, is an example of an organismic system.

  8. Homochirality - Wikipedia

    en.wikipedia.org/wiki/Homochirality

    If one takes, for example, alanine, which has a small methyl group, and phenylalanine, which has a larger benzyl group, a simple question is in what aspect, L-alanine resembles L-phenylalanine more than D-phenylalanine, and what kind of mechanism causes the selection of all L-amino acids, because it might be possible that alanine was L and ...

  9. Alternative abiogenesis scenarios - Wikipedia

    en.wikipedia.org/wiki/Alternative_abiogenesis...

    A scenario is a set of related concepts pertinent to the origin of life (abiogenesis), such as the iron-sulfur world.Many alternative abiogenesis scenarios have been proposed by scientists in a variety of fields from the 1950s onwards in an attempt to explain how the complex mechanisms of life could have come into existence.